Category Archives: High Potency API

High-potency active pharmaceutical ingredients (HPAPIs) are compounds used in the production of pharmaceutical drugs that have a high degree of pharmacological activity. These compounds are typically used in small quantities and are known to have the potential to cause harm to humans at very low doses. HPAPIs are often used in the treatment of serious and life-threatening diseases such as cancer, autoimmune disorders, and viral infections. Due to their high potency, HPAPIs require specialized handling and manufacturing processes to ensure the safety of workers and the general public.

Lurbinectedin

Posted on April 13, 2023 by Thomas Brooks

Lurbinectedin is a chemotherapy drug used to treat cancer. It belongs to the class of drugs called alkylating agents and works by interfering with the DNA in cancer cells, preventing them from dividing and growing. This drug is primarily used Continue reading Lurbinectedin→

Eribulin Mesylate

Posted on April 13, 2023 by Thomas Brooks

Eribulin is a chemotherapy drug used to treat certain types of cancer, including breast cancer and liposarcoma. It is a microtubule inhibitor that works by stopping cancer cells from dividing and growing. Brick42, together with partners has a fully developed, Continue reading Eribulin Mesylate→

On-shore High Potency Pharma Manufacturing in the US and EU

Posted on November 12, 2022 by Thomas Brooks

For many years, there has been a shift towards outsourcing chemical pharmaceutical manufacturing to countries such as China and India, where labor is cheaper. While this has resulted in cost savings for pharmaceutical companies, it has also led to concerns Continue reading On-shore High Potency Pharma Manufacturing in the US and EU→

Trabectedin API

Posted on April 13, 2022 by Thomas Brooks

Trabectedin is an anti-tumor drug that is mainly used to treat soft tissue sarcoma and ovarian cancer. It is a natural compound that was originally discovered in the 1960s by Spanish scientists from the marine tunicate Ecteinascidia turbinata. The drug Continue reading Trabectedin API→

High Potency Active Pharmaceutical Ingredients for Generic Drugs

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Posted on March 12, 2019 by Thomas Brooks

Rare diseases affect a small percentage of the population and often have limited treatment options. However, the availability of High Potency Active Pharmaceutical Ingredients (HPAPIs) for generic drugs has played a critical role in addressing these diseases. HPAPIs are highly Continue reading High Potency Active Pharmaceutical Ingredients for Generic Drugs→